Our manuscript titled "The Parkinson’s disease protein alpha-synuclein is a modulator of Processing-bodies and mRNA stability" has been published today in Cell. In this study led by Dr. Erinc Hallacli, we newly showed that alpha-synuclein directly modulates Processing-bodies (P-bodies) that...
News
Fri, 02/25/2022
In this paper, we applied a novel pathway-based approach to investigate the role of rare genomic variants in infectious purpura fulminans (PF), an extreme phenotype of sepsis with hyperinflammation and coagulopathy for which the role of inherited risk factors is currently unknown. We found a...
Thu, 10/14/2021
We will be presenting a talk titled "Network-based genomics approaches for rare variants in synucleinopathies" at the IPDGC October 2021 meeting.
Fri, 06/11/2021
Check out our latest preprint exploring "The missing link between genetic association and regulatory function."
Sat, 08/22/2020
Talk title: Functional Interpretation of Omics Data for Health and Disease
Abstract: Recent advances in next-generation sequencing technologies have resulted in an explosive growth of diverse omics data. Functional interpretation of such data faces challenges due to their size, multi-...
Fri, 08/07/2020
The Bangladeshi Perspective is an initiative by a Bangladeshi Harvard undergraduate to showcase the talent and narrative stories of inspirational Bangladeshis worldwide and make it accessible to a general public. It's LinkedIn page can be found at...
Thu, 04/02/2020
Talk Title: "A Novel Test for Trend in Rare Variant Burden of Functional Modules Implicated in Diseases"
Mon, 02/24/2020
In this paper, we introduce Carnelian, an end-to-end pipeline for metabolic functional profiling uniquely suited to finding functional trends across diverse datasets. Carnelian is able to find shared metabolic pathways, concordant functional dysbioses, and distinguish Enzyme Commission (EC)...
Sat, 09/07/2019
Title of the talk: Uncovering hidden functional patterns across diverse study populations from whole metagenome sequencing reads with Carnelian
Abstract:
Microbial populations exhibit functional changes in response to different ambient environments. Comparative metagenomic studies...
Fri, 11/30/2018
I gave an invited talk at the Frontiers in Mucosal Immunology (FIMI) symposium at Harvard Medical School on Nov 30.
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